Topic: blood buffer system Exercise 1

Patient M., 54 years old, was admitted to the hospital in serious condition. Complains of general weakness, severe weight loss. In the last 5-6 days, after almost every meal, he feels pain in the epigastric region, accompanied by vomiting.

In the study of АBS (acid-base state) revealed:

pH art. blood = 7.55

pCO₂ = 60 mm Hg. Art.

SB = 50 mmol / L

BE = 18 mmol / l

Make a conclusion about the nature of the violation of the CBS. What is the possible reason for the violation of CBS in this patient? What is the reason for the increase in pCO₂.

Conclusion: Decompensated relative metabolic alkalosis. The reason may be related to the loss of chloride during vomiting. ↑ pCO₂ is due to hypoventilation.
Normal values ​​of the main indicators of CBS arterial blood

№ п/п	Index	Norm
		Men	Women
1	arterial blood pH	7.36-7.42	7.37-7.42
2	pCO2 of arterial blood (mm Hg)	35.8-46.6	32.5-43.7
3	Standard bicarbonate SB, mmol / l	21.3 — 24.8
4	Shift of buffer bases BE, mmol / l	от -2.4 до +2.3	от -3.3 до +1.2

1. Indicate the most important patterns of biomedical electrolytes

2. Describe the types of blood buffer systems

3. Compare the patient's data in the study of the ABS with the normal values of the main indicators of ABS arterial blood