Международный научный журнал №7(100), часть «Научный Фокус» ноября, 2023 Международный современный научно-практический журнал Научный Фокус


MORPHOLOGICAL CHANGES OF GASTRIC WALLS DURING POSTNATAL



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Журнал «Научный Фокус» №7 часть 2

MORPHOLOGICAL CHANGES OF GASTRIC WALLS DURING POSTNATAL 
ONTOGENESIS WHEN FEEDING ON PALM OIL 
Farangiz Azamatovna Nazarbaeva 
Tashkent medical academy 
Aim: obesity is currently considered one of the most common chronic diseases in 
the world. It should be not-ed that nutrition obesity accounts for 97% of all forms of 
body weight. This is largely due to the change in daily diet and lifestyle. The relevance 
of this problem is the main factor in obesity is that associated with metabolic 
disorders. 
Significantly, it increases the risk of developing many diseases and pathological 
processes. Obesity reduces resistance to colds and infections and increases the risk of 
complications in injuries significantly. Analyzes carried out by the World Health 
Organization in 23 countries, importing palm oil have shown that the mortality rate 
associated with cardiovascular diseases in these countries is very high. The volume of 
palm oil imported into our country is in-creasing from year to year. According to 
reports, the import of palm oil into Uzbekistan began in the 2000s, initially, 5 thousand 
tons. Palm oil, gastric, morphological, hematoxylin eosin, Van-Gizone. To study the 
mucous and muscle 31 layers of the stomach, the dynamics of progress, 
microcirculatory vessels, tissue structures, development and formation in postnatal 
ontogenesis and exposure to palm oil. 
Materials and methods: the object of our morphological experimental study is the 
gastric, mucous and muscle layers of the gastric wall of rats, microcirculatory organ, 
internal organ vessels, gastric mass. Micropreparations-hematoxylin eosin, Van-Gison, 
Weigert Methods: The method is morphometry of the floors of the gastric wall and the 
thickness of the vascular wall is used. The variation-statistical method is used. A total 
of 240 white laboratory rats are taken for research. They are studied at different 
periods of postnatal ontogenesis: 3, 7, 14, 21, 30, 60, 90, 120, 180 daily. Rats are 
classified into 2 groups: 
Group 1 control group 
Group 2 experimental group Results: our studies show that rat children those fed 
experimental palm oil are characterized by different levels of morphological 
differentiation in the structure of the mucous and muscle layers of the gastric wall. 
- Development of methodological recommendations named changes in the 
morphological and morphometric parameters of the stomach when excessive 
consumption of palm oil in the long term. 
- Medical universities are explained by the fact that in the educational process 
they use Anatomy, histology, patalogical Anatomy, pharmacology as a new source of 
information when giving lectures and conducting practical classes, in the independent 
work of students. 


Международный научный журнал № 7(100), часть 2 
«Научный Фокус» ноября, 2023 
238 
- Early diagnosis of elementary obesity, the degree of its development, a decrease 
in complications, allows patients to improve their quality of life. 
Conclusion: the scientific significance of the results of the study reveals the 
complex mechanisms of digestive processes that occur in the body, at different age 
periods, when feeding with palm oil, the results show the characteristics of gastric 
ontogenesis, microcirculatory self and the development of blood vessels of the internal 
organ, its formation depending on age and from a new point of view, the gastric wall is 
explained by the fact that it allows you to expand the level of theoretical knowledge 
about histotopography and its structural changes and is used in various areas of 
scientific research. 
Thus, in the structure of the mucous and muscle layers of the gastric wall, a 
morphofunction change in the gastric wall of the newborn and the developing organ is 
being studied. 
For the first time, during different periods of postnatal ontogenesis and after 
prolonged excessive consumption of palm oil, morphological and morphometric 
indicators of the floor of the gastric wall are characterized by age-related 
characteristics. 


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