BOLALARDA PROFIL PATOLOGIYASINI SHAKLLANISHIGA LOR A'ZOLARNING

Международный научный журнал № 7(100), часть 2 
«Научный Фокус» ноября, 2023 
31 
Nazirov Dilmurod Muxtorali o‘g‘li 
A.G. Ganiyev
Ilmiy raxbar, dots.nt Andijon davlat tibbiyot instituti 
Izoh: Ushbu maqolada bolaning sog‘lig‘ini tavsiflash usuli sifatida bolalar aholisini 
profilaktik tekshiruvlarning avtomatlashtirilgan tizimi (ASPOND) ishlatilgan. LOR - 
patologiyasi bo‘lgan bolalarda nevrozlarning turli shakllari, tiklar va diqqat etishmasligi 
giperaktivligi buzilishi o‘zaro bog‘liq bo‘lishi mumkin. Bolaning somatik patologiyasi 
profilini hisobga olgan holda, surunkali LOR kasalliklarini davolashni oldini olish yoki 
optimallashtirish, polifarmasiyadan qochish, bolaning ota-onasi turli mutaxassisliklar 
shifokorlariga tashrif buyurish uchun vaqtni yo‘qotish, asossiz yoki aksincha, asossiz 
kechikish. LOR kasalliklarini jarrohlik davolash. 
Kalit so‘zlar: bolalar, LOR a’zolari kasalliklari, korrelyatsion bog‘lanish. 
Relevance. The formation of a chronic ENT disease in a child cannot be 
considered without forming a profile of the entire pathology or deviations in physical 
health [3,4,9]. 
At the same time, there are few works devoted to a comprehensive pediatric 
examination of children with diseases of the ENT organs. Series of works by E.V. 
Borzov is of interest, dedicated to the study of the characteristics of the functional 
state of the central nervous system in children with adenoids, clinical and 
hematological characteristics [1,2,4]. There is a good evidence base to explain the 
association of neurocognitive impairment in children with adenotonsillar hypertrophy 
[5,8]. Most of the works in the “somatic” direction concern the study of the 
cardiovascular system with hypertrophy of the pharyngeal and palatine tonsils. A 
connection has been established between pathology and enlargement of the left 
and/or right ventricle [9], increased pressure in the pulmonary artery [10], sinus 
tachycardia and atrioventricular block [6], and an increase in the frequency of mitral 
regurgitation [4]. Diseases associated with chronic tonsillitis are diverse and can have 
both neuro-reflex and infectious-allergic components [3, 4, 6]. 
Goals of work. We conducted a study of the correlation between chronic ENT 
pathology and other diseases, taking into account age dynamics and hereditary 
predisposition in 307 children. By identifying the presence of a connection, assessing 
its strength and level of reliability, it is possible to determine the likelihood of the 
formation of a characteristic pathology profile in a child with chronic diseases of the 
ENT organs. 
Materials and methods. The Automated System of Preventive Examinations of the 
Child Population (ASPOND) was used as a way to describe the child’s health [7]. The 
approach is based on the construction of a pathology profile, which is a set of 
anamnestic signs assessed by a group of specialists, characteristics of an objective 
examination, complaints sorted into groups of nosologically forms. The pathology 

Международный научный журнал № 7(100), часть 2 
«Научный Фокус» ноября, 2023 
32 
profile is a diagram on which groups of nosologically forms are displayed along the 
abscissa axis, and points of expert assessment are displayed along the ordinate axis. In 
fact, the value on the ordinate axis reflects the probability of detecting pathology in the 
corresponding group of nosologically forms, and the whole pattern reflects the degree 
of complexity of the lesion or the severity of the condition. 
The software of the complex allows you to identify deviations in the state of 
health in the main forms of childhood pathology in the following courses: allergology, 
vasocardiology, gastroenterology, hematology, dermatology, immunology, cardiology, 
otorhinolaryngology, neurology, nephrology, ophthalmology, dittology, pulmonology, 
rheumatology, dentistry, pathophysiology, surgery, endocrinology The main 
conclusion of ASPON-D is a pathology profile with a score proportional to the volume 
of chronic abnormalities in a child in the pathology class. 
We studied 3 groups of children of the same age (age range 2-18 years, average 
age 7.4+-1.2 years) with the same ratio of girls and boys (boys - 48-62%). 
Group 1 consisted of 78 children with chronic ENT pathology (adenoids, 
hypertrophy of the palatine tonsils, chronic tonsillitis, chronic rhinosinusitis, 
polyposis, deviated nasal septum, chronic otitis, secretory otitis) in children living in 
Andijan. 
Group 2 - 45 children from the population of Andijan, examined during 
preventive examinations. 
Group 3 – 184 children, examined during preventive examinations of the 
population of the Andijan region. 
Group 2 was introduced in order to minimize deviations caused by the inability to 
use multiple correlation due to the nonparametric nature of expert assessments of the 
list of ASPND signs. This drawback significantly complicates the assessment of the 
relationship in the case of many control factors. The introduction of a control group, 
which includes both healthy children and those with other types of pathology, but 
without ENT pathology, allows us to minimize the impact of this deficiency. Group 3 
was formed to neutralize the consequences of fairly high-quality medical care in 
Andijan, smoothing out the severity of signs of pathology. 
This group includes children living in the Andijan region with varying, but on 
average quite low, levels of medical care, which makes it possible to more fully identify 
the range of real correlations. 
To identify correlations between chronic ENT pathology and the profile of 
somatoneurological diseases in a child, a nonparametric criterion was used - the 
Spearman pairwise correlation coefficient. 
Research results. Despite the fact that most of the identified correlations are 
classified as weak (the correlation coefficient does not exceed 0.5), significantly more 
correlations were identified in children with chronic ENT pathology compared to the 
control group, and correlations between ENT pathology and other types of pathology 
strength; in particular, in 4 cases (classes neurology, nephrology, rheumatology, 

Международный научный журнал № 7(100), часть 2 
«Научный Фокус» ноября, 2023 
33 
immunology) the value of the correlation coefficient exceeded 0.4. It should also be 
noted that a significant connection between chronic ENT pathology and cardiac 
(p=0.000) and immunological (p=0.000) pathology, found during examination of 
children with chronic ENT diseases, was not found in the control group. 
Carrying out mathematical modeling in order to determine the role of the above-
mentioned classes in the formation of clusters of combined somatic and ENT 
pathologies revealed that diseases of the classis’s “cardiology”, “allergology”, “speech 
therapy”, “immunology”, “neurology”, “rheumatology” have the greatest information 
content. It should be noted that the gender of the child does not matter for 
classification. A study of the dependence of chronic ENT pathology and other types of 
pathology on age also yielded interesting results. The most stable classes of pathology 
associated with chronic ENT pathology in all age groups are “cardiology”, “allergology” 
(“immunology”), “rheumatology”, “neurology”. The connection with the “speech 
therapy” class is maximum in the middle age group (7–10 years). In a multivariate 
analysis, associations with the classis’s “nephrology”, “gastroenterology”, 
“pulmonology”, “orthopedics”, “nutrition”, in contrast to the assessment of pairwise 
connections, become insignificant, since they are obviously realized indirectly. In 
future publications, we plan to cover in detail the pathology profile and the most 
common nosologically units and syndromes for diseases such as chronic tonsillitis, 
adenoids, chronic sinusitis, deviated nasal septum, secretory otitis media and clinical 
diagnostic algorithm. to verify the condition of a child with chronic ENT according to 
the pathology profile and construct stages of treatment taking into account this profile. 
Conclusions: Chronic pathology of the ENT organs, which develops in childhood, 
significantly deforms the profile of the child’s pathology. 
The most consistent connections have been identified between the pathology of 
the ENT organs and such classes of diseases as allergies, cardiorheumatology and 
neurology. 
Allergies, which are more widespread than indicated in official statistics, can 
often be the only universal pathogenesis link in the formation of diseases such as 
adenoids, chronic rhinosinusitis, polyposis, exudative otitis media in combination with 
bronchial asthma, allergic dermatitis. 
Diseases of the cardiorheumatological class, traditionally associated with chronic 
tonsillitis, appear to be undergoing pathomorphosis. The number of pronounced forms 
of rheumatism has decreased. To diagnose this class of diseases at the present stage, it 
is necessary to use more subtle markers detected using ultrasound, Holter monitoring, 
studying the structure of the heart rhythm, and immunological studies. 
In children with ENT pathology, various forms of neuroses, tics, and attention 
deficit hyperactivity disorder may be interrelated. 
Taking into account the profile of the child’s somatic pathology allows us to 
prevent or optimize the treatment of chronic ENT diseases, avoid polypharmacy, loss 

Международный научный журнал № 7(100), часть 2 
«Научный Фокус» ноября, 2023 
34 
of time for the child’s parents to visit doctors of various specialties, unjustified or, 
conversely, unjustified delay. surgical treatment of ENT diseases. 

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