Статья Год издания: 2000 Издательство
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| 126. Pierpaoli W., Regelson W. Pineal control of aging: effect of melatonin and pineal grafting on aging mice // Proc. Natl. Acad. Sci. USA.-1994.- Vol. 91.- P. 787-791.
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Petrov Research Institute of Oncology, Pesochny-2, St.Petersburg,189646, Russia. E-mail: aging@mail.ru A significant increase of the elderly in populations of developed countries followed by increase morbidity and mortality from main age-related diseases - cardiovascular, cancer, neurodegenerative, diabetes mellitus, decrease in resistance to infections. The concepts of "healthy aging" was stressed as a high priority by experts of the UN Program on Aging project "Research Agenda on Aging for the 21th Century". Obviously the development of means of the prevention of the premature aging of humans is the crucial for the realization this program. However available data on such kind means rather sacrce, contradictory and often are not relable from the points of view of the adequacy of the experiments to current scientific requirements as well as the interpreation of the results and safity. In the review the critical analysis of the experiments on the life span extension by drugs and some other means and recommendations for its practical use have been done. The main attention was paied to adverse and unfavourable effect of these means, in first, to development of tumor. Key words: Life span, premature aging, prevention, longevity, geroprotectors, cancer. жүктеу/скачать 232.5 Kb. Достарыңызбен бөлісу:
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