1. Объем резюме увеличить минимум до 1000 знаков с пробелами.
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ASSOCIATION OF PERIODONTAL DISEASES WITH ACUTE CORONARY SYNDROME
Agababyan I.R., Rizaev J.A., Nasretdinova M.T.
Samarkand state medical university
Conflict of interest: not stated.
Authors' contribution: literature review, data selection and analysis, research
scientific guidance - Agababyan I.R.; Rizaev J.A.;
concept and desing – Nasreddinova M.T.;
Submitted:
Accepted:
Contacts:irina.agababyan17@gmail.com
Abstract:
Objective: Due to their prevalence in the present, cardiovascular diseases, as well as inflammatory periodontal diseases, are considered as social diseases. So, in Uzbekistan over the past 2 years, the number of patients with cardiovascular diseases aged 30 to 70 years is 53%. They are also one of the most common causes of death worldwide. Periodontal diseases, in turn, are among the most common diseases of the oral cavity and, along with caries, constitute the main cause of tooth loss. In this review, based on numerous randomized and single-blind studies, the association of inflammatory periodontal diseases of varying severity with coronary heart disease, in particular with acute coronary syndrome (ACS), was revealed. In particular, the role of pro-inflammatory cytokines - C-reactive protein, IL-6, IL-8, TNF-a in maintaining the inflammatory process in periodontitis and progression of coronary artery disease is shown. The research is noteworthy and needs to be studied more closely.
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